Brain Network

BRAIN NETWORK
The role of the hippocampus in associative memory is the establishment of long-term, declarative memories. For example, memories for facts, names, and life experiences. Damage to the hippocampus leads to loss of ability to convert short-term memory to new long-term memories.
brain network
Brain Network
Stage 1 A two-dimensional interface with a rodent hippocampal brain slice. Electronic stimulation is induced to replicate neuron activity. Single input/output, non-spontaneous activity.

Stage 2 A three-dimensional interface with a behaving rodent hippocampus. Stimulation is driven by the actual brain environment. Multiple input/output, spontaneous activity.

Stage 3 A three-dimensional interface with a behaving human hippocampus. Stimulation is driven by the actual brain environment. Multiple input/output, spontaneous activity.
Clinical applications of a biomimetic implant which replaces damaged brain function might be Stroke [preferential damage to CA1 neurons], Brain Trauma [preferential damage to hippocampal hilar neurons], Epilepsy [preferential damage to CA3 pyramidal cells], and Alzheimer�s Disease [preferential damage throughout the hippocampus].

Replacing a Component of the Hippocampal Neural Circuit with a Biomimetic VLSI Device

A candidate device is a TMSC 0.18 micron CMOS (MOSIS) microchip.

Its circuitry includes A/D and D/A controllers, signal processing of input waveforms for population spike waveform identification and amplitude measurement.

Its footprint allows expansion to 100 CA3 models if required, i.e., replacement of 100 hippocampal circuits.
A brain slice of the hippocampus
It is the goal of research from the Biomedical Engineering lab of Dr. Theodore W. Berger at USC.
Electrode array feeds neural activity in the hippocampus to the chip which delivers output to the rest of the brain, bypassing damaged tissue.

Its function will be to mimic the structure of the nerve tissue in the hippocampus by placing multiple electrodes on an array, to listen for incoming neuron activity, and then to stimulate electrodes to deliver the appropriate output to the rest of the brain — potentially restoring memory function for patients with tissue damage.

brain implant


The implant is currently being tested . A first test of the implant in general humans is projected in the next 2 years.

The research has been honored most recently by EETimes, chosen for inclusion in the “Great Minds, Great Ideas” program. Profiled by Newsweek in 2005, the research was hailed as a “Next Frontier.” 
Read Press



Dr. Berger’s research uses experimental and theoretical approaches to develop models of mammalian neural systems, focusing currently on the hippocampus area of the brain, essential for learning and memory functions. The purpose is to study the way living hippocampal neurons behave and exchange electrical signals and to adapt this behavior to a synthetic device; a computer chip.

Already successful on a number of levels, the research intends to provide a hitherto unavailable treatment for damaged brain function, either a result of injury or a result of disease, like Parkinson’s and Alzheimer’s disease.
he product of this research has many names: neural prosthesis, biomimetic implant, brain chip, biotech implant, and embedded microchip.
Electrode array feeds neural activity in the hippocampus to the chip which delivers output to the rest of the brain, bypassing damaged tissue

Its function will be to mimic the structure of the nerve tissue in the hippocampus by placing multiple electrodes on an array, to listen for incoming neuron activity, and then to stimulate electrodes to deliver the appropriate output to the rest of the brain — potentially restoring memory function for patients with tissue damage.

The implant is currently being tested in rats and will eventually be tested in other animals. A first test of the implant in humans is projected in the next five years.

The research has been honored most recently by EETimes, chosen for inclusion in the “Great Minds, Great Ideas” program. Profiled by Newsweek in 2005, the research was hailed as a “Next Frontier.” 
Read Press
Through the neuromorphic, multi-site electrode array, the VLSI device interfaces with a brain slice to functionally replace the  subregion of the hippocampus and replace whole-circuit brain dynamics.
brain-network

Through the neuromorphic, multi-site electrode array, the VLSI device interfaces with a brain slice to functionally replace the CA3 subregion of the hippocampus and replace whole-circuit brain dynamics.

Conceptual BCI system with various kinds of Neurofeedbacks. In the development of a BCI we need to handle two learning systems: The machine should learn to discriminate between different complex patterns of brain activity as accurate as possible and the BCI users should learn via different neurofeedback configurations to modulate their EEG activity and self-regulate or control them.

Another promising extension of BCI is to incorporate various neurofeedbacks to train subjects to modulate EEG brain patterns and parameters such as ERPs, ERD, SMR, P300 or slow cortical potentials (SCPs) to meet a specific criterion or to learn self-regulations skills. The subject then changes their EEG patterns in response to some feedback. Such integration of neurofeedback in BCI (Fig. 4) is an emerging technology for rehabilitation, but we believe is also a new paradigm in neuroscience that might reveal previously unknown brain activities associated with behavior or self-regulated mental states. The possibility of automated context-awareness as a new interface goes far beyond the standard BCI with simple feedback control. We hope to develop the next level of BCI system using neurofeedbacks for some selective cognitive phenomena. To do so, we need to rely increasingly on findings from other disciplines, especially, neuroscience, information technology, biomedical engineering, machine learning, and clinical rehabilitation.

brain computer interface

8 Responses to Brain Network

  1. Anders UK says:

    Webbplats:https://minduploadingproject.org/Företagsfakta:
    MIND UPLOADING is the hypothetical technology of transferring a biological brain into a computer system. Sufficient computer power for human brain simulation is expected between 2013-2025.
    – It means mind uploading could be reality within twenty years.
    – It means we could live forever in virtual worlds generated inside computer systems.
    – It means we could live anywhere in the universe, wherever computer systems are able to work.
    All of this can be realised within tens years IF SOCIETY DEMANDS IT. (läs mer)
    Vision:If you want to accelerate the creation of this technology, give your “YES” for Mind Uploading Technology here:Produkter:https://www.minduploadingproject.org/blog/2010/01/yes-for-mind-uploading-technology.html

  2. Bill N E.U says:

    yes, really frightening stuff. I can’t believe no trails at least since they say it’s the same drug. A radio transmitter really makes it a LOT different. I don’t want a Radio transmitter in my body. It seems that we are to be watched, tracked and made sure that we do what someone else says we must. There was a hearing this Spring in the Senate on Aging discussing just how great this all would be!! They are trying to have broadband over the electric wires, pills that track, a medical ‘force’ that makes sure you take your medications etc. This is just one of the first times I saw it mainstream. We really do have to stop this!